Authors : Zaid Alsafi · Alice Snell · Jonathan P. Segal

International Journal of Colorectal Disease (2022) 37:357–364

Originally published on Springer  https://link.springer.com/article/10.1007/s00384-021-04067-6

Abstract

The ileoanal pouch (IPAA) provides patients with ulcerative colitis (UC) that have not responded to medical therapy an option to retain bowel continuity and defecate without the need for a long-term stoma. Despite good functional outcomes, some pouches fail, requiring permanent diversion, pouchectomy, or a redo pouch. The incidence of pouch failure ranges between 2 and 15% in the literature. We conducted a systematic review and meta-analysis aiming to define the prevalence of pouch failure in patients with UC who have undergone IPAA using population-based studies.